NAD+ Therapy:
Restore the fuel of every cell in your body.
Easy at home. Felt everywhere.
Self-administer in seconds. Within weeks, patients report sharper focus, faster recovery, and energy that holds through the afternoon.
Choose your NAD+ protocol.
Both options include physician review within 24 hours. No hidden fees. Cancel anytime.
First charge after physician approval
- 1000mg NAD+ vial, compounded monthly
- Provider-reviewed protocol
- Temperature-controlled shipping
- Syringes + administration guide
- Direct provider messaging
- Cancel anytime — no contracts
Try before you subscribe
- 1000mg NAD+ vial, single shipment
- Provider-reviewed protocol
- Temperature-controlled shipping
- Syringes + administration guide
- Direct provider messaging
- Upgrade to subscription anytime
🔒 HIPAA-protected medical intake · Card processed by Authorize.net (PCI-DSS Level 1)
What NAD+ does, in plain English.
NAD+ is the molecule your cells use to convert food into ATP — the energy currency that powers every breath, every thought, every muscle contraction. It's also the fuel for two repair systems that keep you young: sirtuins (longevity proteins) and PARPs (DNA repair).
Why levels plummet with age
By age 40, your cells produce NAD+ slower than they consume it. By age 60, systemic levels can fall by 50%. This shortage creates a state called "pseudohypoxia" — your cells behave as if they're oxygen-starved, even when they're not. Mitochondrial communication breaks down. Genomic repair slows. The visible markers of aging — fatigue, weight gain, slower recovery, thinner skin, cognitive fog — emerge.
Restoring NAD+ doesn't just refill a tank. It reactivates the entire metabolic network that depends on it — sirtuins that protect mitochondria, PARPs that repair DNA, and the signaling pathways that orchestrate cellular renewal. It's why patients consistently report feeling "the version of themselves from 10 years ago."
Where NAD+ restoration shows up in your body.
High-energy tissues — brain, heart, muscle, skin — are the first to feel the depletion and the first to feel the restoration.
Cognitive Clarity
NAD+ restoration reduces beta-amyloid plaque formation and rebuilds neuronal mitochondrial morphology. Patients report sharper thinking, better memory recall, and reduced afternoon brain fog within weeks.
Metabolic Efficiency
Activates the SIRT1/SIRT3-mediated mitochondrial unfolded protein response, improving insulin sensitivity and oxygen utilization. Translates to easier weight management and sustained energy.
Muscle & Recovery
Rejuvenates muscle stem cells through the Sirt1-PGC-1α axis. Restores mitochondrial signaling needed for strength, endurance, and faster post-workout recovery.
Skin & Longevity
Inhibits MMP-1 collagen breakdown, repairs UV-induced DNA damage, and reduces cellular senescence. The "Inside-Outside" approach modern dermatology now considers foundational.
Sustained Energy
Directly supports Complex I of the electron transport chain — the gatekeeper of ATP production. Cellular energy without the crash of caffeine or stimulants.
Inflammaging Defense
Counters the CD38-driven inflammatory "sink" that aggressively degrades NAD+ with age. Restoring balance shifts the body from chronic inflammation toward repair.
How to start NAD+ therapy.
No clinic visit. Complete a medical questionnaire — a board-certified physician reviews your protocol — your NAD+ ships from a US-licensed compounding pharmacy.
Medical Questionnaire
Complete a brief intake from home. Five minutes — covers medical history, current medications, and your goals.
Physician Review
A board-certified physician reviews your protocol within 24 hours. Reaches out if anything needs clarifying.
Compounded & Shipped
US-licensed pharmacy compounds your NAD+ and ships overnight in temperature-controlled packaging.
Self-Administer
Subcutaneous injection at home, 2–3x per week per protocol. Includes detailed instructions and provider access for questions.
Your clinical restoration timeline.
Individual results vary based on baseline NAD+ levels, age, and protocol. These are the most consistent patterns we observe.
Enhanced mental clarity
Earliest patient reports describe sharper focus and increased bioenergetic capacity — particularly in the afternoons when energy typically dips.
Measurable NAD+ rise
Quantifiable increases in blood NAD+ and NAAD biomarkers. Energy stabilizes throughout the day. Sleep quality improves for most patients.
Cumulative systemic benefits
Insulin sensitivity improvements, increased muscle recovery rate, dermatological brightness, and reduced markers of inflammaging emerge as the cellular repair systems reach full activity.
Maintenance protocol
Once peak restoration is achieved, your provider adjusts dosing for long-term maintenance. Many patients continue indefinitely as part of a longevity protocol.
Start your NAD+ protocol today.
Auto-ships monthly. Cancel anytime by email or phone. No long-term commitments.
First charge after physician approval
- 1000mg NAD+ vial, compounded monthly
- Provider-reviewed protocol
- Temperature-controlled shipping
- Syringes + administration guide
- Direct provider messaging
- Cancel anytime — no contracts
Try before you subscribe
- 1000mg NAD+ vial, single shipment
- Provider-reviewed protocol
- Temperature-controlled shipping
- Syringes + administration guide
- Direct provider messaging
- Upgrade to subscription anytime
🔒 HIPAA-protected medical intake · Card processed by Authorize.net (PCI-DSS Level 1)
The cellular biology behind NAD+ therapy.
For patients who want to understand why physician-supervised NAD+ replenishment outperforms over-the-counter supplements.
The Salvage Pathway
Your cells primarily make NAD+ by recycling Nicotinamide (NAM) through the rate-limiting enzyme NAMPT. Aging slows this pathway — supplementing with NR or NMN bypasses the bottleneck.
Subcellular Localization
NMNAT enzymes that finalize NAD+ synthesis exist in three forms: NMNAT1 (nucleus), NMNAT2 (cytosol/Golgi), and NMNAT3 (mitochondria). Effective therapy must serve all three compartments.
Sirtuins — The Longevity Proteins
SIRT1, SIRT3, and SIRT6 are NAD+-dependent. When NAD+ is scarce, sirtuins shut down — directly compromising mitochondrial health, DNA repair, and stem cell rejuvenation.
PARPs — DNA Repair Crews
Every time UV light or oxidative stress damages your DNA, PARP1/2 jump in to repair it. They consume massive amounts of NAD+ — chronic damage can deplete 50% of cellular NAD+ alone.
CD38 — The NAD+ Destroyer
This enzyme expands with chronic inflammation and aggressively hydrolyzes both NAD+ and its precursors. Inflammaging creates a metabolic sink that physician-supervised therapy works to counter.
NAAD Biomarker
A sensitive indicator of increased NAD+ synthesis. Subcutaneous and IV protocols rapidly elevate this marker — measurable proof your cells are converting the molecule into active cofactor.